Blog Posts | Joshua Berkowitz

34 Articles

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AlphaFold: Five Years That Transformed Science Forever

AlphaFold, Google DeepMind’s groundbreaking artificial intelligence, is unlocking secrets of the molecular world at the speed of thought by solving the long-standing puzzle of protein folding. AlphaFo...

AI in science AlphaFold biological research DeepMind digital biology drug discovery protein structure

Nov 27, 2025

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Expert Human Feedback Is Changing AI-Driven Drug Discovery

AI has shown immense potential in many fields, but drug discovery has long stood apart due to its complexity. Insilico Medicine is bridging this gap with its Reinforcement Learning with Expert Human F...

biotechnology Chemistry42 drug discovery expert feedback generative AI machine learning pharmaceutical innovation reinforcement learning

Nov 16, 2025

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MIT's miBrain 3D Human Brain Model Is Unlocking Neural Complexity in a Dish

Scientists have long dreamed of replicating the intricacies of the human brain in the lab. Now, MIT researchers have turned this vision into reality with the Multicellular Integrated Brains (miBrains)...

Alzheimer's brain model drug discovery neuroscience personalized medicine stem cells tissue engineering

Nov 13, 2025

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Deep Learning Resurrects Ancient Antibiotics: Mining Extinct Proteomes for Modern Medicine

In a groundbreaking fusion of paleobiology and artificial intelligence, researchers from the University of Pennsylvania have pioneered a revolutionary approach to combat the escalating global antibiot...

antibiotic discovery antimicrobial resistance artificial intelligence computational biology deep learning drug discovery extinct organisms machine learning molecular de-extinction paleogenomics

Nov 4, 2025

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Papers

GraphBAN Marries Graphs and LLMs to Predict New Compound-Protein Interactions

Understanding how small molecules interact with proteins is a cornerstone of modern drug discovery. These compound–protein interactions (CPIs) determine whether a candidate molecule can modulate a bio...

BAN CDAN compound-protein interactions domain adaptation drug discovery graph neural networks knowledge distillation

Nov 2, 2025

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BoltzGen: Transforming Protein Binder Design with Open-Source Generative AI

Designing protein and peptide binders for any biomolecular target once seemed out of reach, especially for novel or highly complex molecules. Today, BoltzGen is changing that narrative. This innovativ...

binder discovery biotechnology drug discovery generative AI MIT research open source protein design structure prediction

Oct 30, 2025

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Lilly’s AI Factory Is Accelerating the Future of Drug Discovery with NVIDIA Blackwell and DGX SuperPOD

What if we could develop new life saving medicines in months instead of years. Lilly partnerig with NVIDIA to turn this vision into reality by launching the pharmaceutical industry's largest AI factor...

AI factory biomanufacturing DGX SuperPOD digital twins drug discovery NVIDIA Blackwell precision medicine

Oct 30, 2025

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Google’s Cell2Sentence C2S-Scale 27B AI Is Accelerating Cancer Therapy Discovery

Artificial intelligence is setting a new standard in cancer research, with Google's C2S-Scale 27B model leading the way. This advanced AI formulates innovative, testable hypotheses that could shape th...

biomedical AI cancer therapy drug discovery Gemma Google AI immunotherapy model validation single-cell analysis

Oct 18, 2025

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SPR Finds Small-Molecule Binders For CHI3L1, A Hard Cancer Target

Cancer cells often rely on proteins that don't behave like typical enzymes to survive and spread. One such protein is CHI3L1 (also called YKL-40) , which cancer cells secrete to communicate with ...

brain cancer cancer CHI3L1 drug discovery glioblastoma small molecules SPR STAT3 surface plasmon resonance YKL-40

Oct 14, 2025

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AI Is Fast-Tracking Precision Antibiotics for a Healthier Gut

Thanks to innovative research from MIT’s CSAIL and McMaster University, researchers are leveraging a generative AI model to rapidly decoded how a novel antibiotics work, opening the door to targeted t...

antibiotics artificial intelligence drug discovery gut health inflammatory bowel disease machine learning microbiome precision medicine

Oct 6, 2025

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How AI Agents Are Changing Scientific Research Workflows

What if you could hand off the repetitive but essential tasks of research like data curation, code writing, or hypothesis testing, to an intelligent digital assistant? AI agents are making this scenar...

AI agents automation collaboration drug discovery large language models research tools scientific research

Oct 6, 2025

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NIH Unveils SOM Center: Pioneering Standardized Organoid Research

The National Institutes of Health is reshaping the landscape of biomedical research with the launch of the Standardized Organoid Modeling (SOM) Center, the nation’s first dedicated hub for organoid de...

animal alternatives artificial intelligence biomedical research drug discovery NIH organoids preclinical models standardization

Sep 26, 2025

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