Blog Posts | Joshua Berkowitz

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Unraveling the Hidden Barrier to Cancer Immunotherapy: The Role of Protein Quality Control in T Cell Exhaustion

Recent research from The Ohio State University Comprehensive Cancer Center has unveiled a crucial, yet previously unrecognized, factor in the struggle against cancer: the breakdown of protein quality ...

biomarkers cancer immunotherapy immune resistance immuno-oncology protein quality control proteotoxic stress T cell exhaustion therapeutic targets

Jan 2, 2026

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News

Unveiling Hidden Cell Subtypes to Transform Cancer Research

CellLENS is a groundbreaking artificial intelligence tool developed by a multidisciplinary team led by MIT designed to precisely identify which immune cells are fighting, helping, or hindering tumors,...

artificial intelligence biomarkers cancer research cell subtypes deep learning immunotherapy precision medicine

Aug 4, 2025

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NMR Spectroscopy Is Transforming Inflammation Diagnostics

Advances in high-resolution Nuclear Magnetic Resonance (NMR) spectroscopy are reshaping how we understand and detect inflammation in the body. Instead of relying on traditional, broad-strokes markers,...

acute inflammation biomarkers cardiovascular risk chronic disease clinical diagnostics inflammation lipoproteins NMR spectroscopy

Jul 24, 2025

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Papers

Benchtop NMR Spectroscopy: Bringing Advanced Lipoprotein Analysis to Every Clinic

What if advanced cardiovascular risk assessment wasn’t limited to elite research facilities? Thanks to recent breakthroughs in benchtop nuclear magnetic resonance (NMR) spectroscopy, that vision is be...

benchtop technology biomarkers cardiovascular risk clinical diagnostics lipoproteins NMR personalized medicine

Jun 15, 2025

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Quick Research Reviews

Unlocking Alzheimer’s Mysteries: How PHGDH Changes the Game

Alzheimer’s disease remains one of the most challenging neurodegenerative conditions, particularly in its late-onset form (LOAD), which strikes millions without clear genetic risk factors. Recent rese...

Alzheimer's amyloid-beta biomarkers neurodegeneration PHGDH therapeutics transcriptional regulation

May 31, 2025

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Quick Research Reviews

FDA Clears First Blood-Based Biomarker Test for Alzheimer's: What It Means for Patients and Providers

Diagnosing Alzheimer’s disease could be as simple as a routine blood draw thanks to the FDA’s recent clearance of the Lumipulse® G pTau 217/β-Amyloid 1-42 Plasma Ratio test from Fujirebio. This innova...

Alzheimer's biomarkers diagnostics FDA clearance Fujirebio neurodegenerative diseases plasma test

May 22, 2025

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News

How Stromal Disruption Could Transform Breast Cancer Risk Detection

Imagine if a simple tissue test could alert doctors to women at greater risk for aggressive breast cancer, long before symptoms appear. That’s the promise behind new research from NIH scientists, who ...

biomarkers breast cancer cancer risk machine learning NIH research prevention stromal disruption women’s health

May 15, 2025

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News

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