Blog Posts | Joshua Berkowitz

14 Articles

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MIT's miBrain 3D Human Brain Model Is Unlocking Neural Complexity in a Dish

Scientists have long dreamed of replicating the intricacies of the human brain in the lab. Now, MIT researchers have turned this vision into reality with the Multicellular Integrated Brains (miBrains)...

Alzheimer's brain model drug discovery neuroscience personalized medicine stem cells tissue engineering

Nov 13, 2025

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MIT Study Reveals How Alzheimer's Disease Disrupts Gene Regulation in the Brain

Alzheimer’s disease is infamous for eroding memory and cognition, but cutting-edge research now uncovers a deeper, cellular struggle that may determine who succumbs and who resists. Scientists at MIT ...

Alzheimer's brain cells cell regulation cognitive decline epigenomics gene expression genomics neuroscience

Sep 12, 2025

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Kitchen Compounds Show Promise for Boosting Brain Health, UC Irvine Study Finds

Is the secret to a healthier, aging brain be found in your pantry? A new study from UC Irvine suggests that natural compounds, already present in common foods, might help fight the effects of aging an...

aging Alzheimer's biomedical research brain health dietary supplements energy metabolism natural compounds neurodegeneration

Aug 11, 2025

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Unraveling the Gender Gap: Why Women Face a Higher Risk of Alzheimer’s Disease

Alzheimer’s disease impacts women at nearly double the rate of men, prompting scientists to explore causes that go far beyond longer life expectancy. While a woman’s lifespan was once considered the m...

Alzheimer's brain health genetics hormones hormone therapy menopause neurology women's health

Jul 28, 2025

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Repurposed Cancer Drugs Show Promise Against Alzheimer’s Brain Damage

Could the answer to reversing Alzheimer’s brain damage already exist on pharmacy shelves? Recent research points to a surprising possibility: some cancer drugs may help fight the devastating effects o...

Alzheimer's brain health cancer drugs clinical trials drug repurposing gene expression irinotecan letrozole

Jul 26, 2025

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Video Games Could Transform Early Detection of Alzheimer’s Disease

Envision a world where playing a video game could reveal Alzheimer’s disease years before symptoms appear. Researchers at Rutgers-Newark are pioneering this possibility, developing computerized games ...

Alzheimer's blood tests brain health clinical trials cognitive testing early detection inclusive research video games

Jun 7, 2025

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Unlocking Alzheimer’s Mysteries: How PHGDH Changes the Game

Alzheimer’s disease remains one of the most challenging neurodegenerative conditions, particularly in its late-onset form (LOAD), which strikes millions without clear genetic risk factors. Recent rese...

Alzheimer's amyloid-beta biomarkers neurodegeneration PHGDH therapeutics transcriptional regulation

May 31, 2025

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Quick Research Reviews

MIT Researchers Chart New Paths for Alzheimer’s Drug Targets Beyond Amyloid

Alzheimer’s disease has challenged the scientific community for decades, especially as treatments focused on amyloid plaques have not delivered the hoped-for results. In a promising shift, researchers...

Alzheimer's computational biology DNA repair drug discovery genetics MIT neurodegeneration RNA modification

May 25, 2025

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FDA Clears First Blood-Based Biomarker Test for Alzheimer's: What It Means for Patients and Providers

Diagnosing Alzheimer’s disease could be as simple as a routine blood draw thanks to the FDA’s recent clearance of the Lumipulse® G pTau 217/β-Amyloid 1-42 Plasma Ratio test from Fujirebio. This innova...

Alzheimer's biomarkers diagnostics FDA clearance Fujirebio neurodegenerative diseases plasma test

May 22, 2025

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How Sugars on Cell Surfaces Could Unlock New Paths to Brain Resilience

What if a crucial piece in the puzzle of brain aging has been hiding in plain sight, overlooked sugars on the surfaces of our brain cells. While past research zeroed in on proteins and DNA, emerging s...

Alzheimer's blood-brain barrier brain aging cell surface sugars cognitive decline drug delivery glycocalyx neurodegeneration

May 22, 2025

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New Genetic Pathways Offer Hope for Alzheimer’s Drug Development

Alzheimer’s disease is a condition that affects millions globally and has traditionally been linked to amyloid plaques in the brain. Most drug development efforts have targeted these plaques but real-...

Alzheimer's computational biology DNA repair drug discovery genetics neurodegeneration RNA modification

May 20, 2025

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AI Revolutionizes How Scientists Map Protein Locations in Human Cells

What if researchers could diagnose diseases or develop breakthrough drugs in a fraction of the time it takes today? Thanks to a cutting-edge artificial intelligence model from MIT, Harvard, and the Br...

Alzheimer's artificial intelligence biomedical research cell biology diagnostics drug discovery machine learning protein localization

May 19, 2025

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