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The Global Endpoint for Claude Models on Vertex AI Boosts AI Reliability

Powering Reliable AI with Global Endpoints

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Developers and businesses can now count on greater reliability and resilience for their AI applications, thanks to the newly launched global endpoint for Anthropic’s Claude models on Vertex AI. This enhancement dynamically routes requests to any available region, ensuring your applications remain accessible and performant even during peak demand or regional outages.

What is Google Vertex AI?

Google's Vertex AI is a comprehensive, cloud-based machine learning platform that streamlines the process of building, deploying, and managing AI applications. It unifies all of Google's cloud services for machine learning into a single environment, providing a complete set of tools for the entire ML lifecycle. 

From data preparation and model training to evaluation and deployment, Vertex AI is designed to accelerate the development of AI solutions. The platform supports both pre-trained models and custom-built solutions, making powerful AI capabilities accessible to developers and data scientists with varying levels of expertise. 

By offering a managed infrastructure, Vertex AI allows teams to focus on creating innovative AI applications without the complexity of managing the underlying hardware and software.

Key Advantages of Global Endpoints

Previously, Claude model requests were limited to specific regions, creating potential for downtime or increased latency if those regions reached capacity. The global endpoint eliminates this single point of failure by intelligently distributing traffic across multiple regions.

  • Higher availability: Multi-region routing reduces the risk of service interruptions.
  • Automatic failover: Requests are seamlessly redirected if a region is unavailable.
  • Consistent experience: Users benefit from stable, fast response times worldwide.

Supported Models and Transparent Pricing

The global endpoint currently accommodates pay-as-you-go usage for several Claude models:

  • Claude Opus 4
  • Claude Sonnet 4
  • Claude Sonnet 3.7
  • Claude Sonnet 3.5 v2

Pricing matches that of regional endpoints, so upgrading won’t introduce unexpected costs. However, provisioned throughput remains exclusive to regional endpoints for now.

Choosing the Right Endpoint for Your Needs

Global endpoints are ideal for most organizations seeking uninterrupted service, unless strict data residency rules apply. Here’s when to use each:

  • Global endpoint: Maximize uptime and flexibility for general use cases.
  • Regional endpoint: Meet regulatory or compliance requirements for data location.

With global endpoints, you have an independent quota, allowing you to scale and manage resources efficiently. If data must stay within specific boundaries, regional endpoints remain essential.

Prompt Caching for Efficiency

The global endpoint fully supports prompt caching. When identical prompts are repeated, the system serves them from the nearest available cache, minimizing both latency and operational costs. If a cache is full in one region, the service intelligently checks others, delivering optimal performance.

Best Practices for Implementation

  • Use the global endpoint as your default to enhance resilience and uptime.
  • Reserve regional endpoints for workloads requiring local data handling.
  • Avoid duplicating requests across both endpoint types to prevent extra charges.
  • Monitor your usage and manage quotas directly in the Google Cloud console as demand grows.

Simple Onboarding Process

Getting started is straightforward: select a supported Claude model and set your API location to “GLOBAL.” The Vertex AI console and detailed documentation make the integration process accessible for teams of any size.

Takeaway

The introduction of the global endpoint for Claude models on Vertex AI marks a significant step forward in delivering scalable, resilient, and efficient AI solutions. By leveraging dynamic routing and advanced caching, organizations can offer dependable AI experiences to users everywhere.

Source: Google Cloud Blog

The Global Endpoint for Claude Models on Vertex AI Boosts AI Reliability
Joshua Berkowitz July 31, 2025
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