Blog Posts | Joshua Berkowitz

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cognitive decline ×

Gene Mutations Drive Dementia in Parkinson’s Disease: New Insights from Yale

When people think of Parkinson’s disease, tremors and movement difficulties often come to mind first. Yet, for many patients, the most distressing effects are cognitive ranging from memory lapses to f...

alpha-synuclein cognitive decline dementia GBA mutations genetics neuroscience Parkinson's disease synaptic function

Sep 30, 2025

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MIT Study Reveals How Alzheimer's Disease Disrupts Gene Regulation in the Brain

Alzheimer’s disease is infamous for eroding memory and cognition, but cutting-edge research now uncovers a deeper, cellular struggle that may determine who succumbs and who resists. Scientists at MIT ...

Alzheimer's brain cells cell regulation cognitive decline epigenomics gene expression genomics neuroscience

Sep 12, 2025

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How Sugars on Cell Surfaces Could Unlock New Paths to Brain Resilience

What if a crucial piece in the puzzle of brain aging has been hiding in plain sight, overlooked sugars on the surfaces of our brain cells. While past research zeroed in on proteins and DNA, emerging s...

Alzheimer's blood-brain barrier brain aging cell surface sugars cognitive decline drug delivery glycocalyx neurodegeneration

May 22, 2025

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