Joshua Berkowitz Unraveling a New Culprit in Alzheimer's Disease: PHGDH Transcriptional Regulation Alzheimer's disease (AD) is a devastating neurodegenerative condition, and while genetic factors like mutations in APP, PSEN, or MAPT and the APOE4 allele are known risk factors, they don't fully expl... BioChemistry NIH Funded
Joshua Berkowitz Machine Learning Helps in Predicting What Genes Do and How They Work Together The vast number of newly sequenced genomes presents a significant challenge: characterizing the functions of the encoded proteins. Traditional methods for assigning protein function often rely on simi... Computer Science Medicine NIH Funded
Joshua Berkowitz Automated Drug Discovery using Multifidelity Bayesian Optimization This research introduces a multifidelity Bayesian optimization (MF-BO) approach to accelerate the automated discovery of drug molecules by effectively leveraging experimental data of varying costs and... Chemistry Computer Science NIH Funded
Joshua Berkowitz A New Weapon Against Superbugs: Scientists Discover Lariocidin, a Lasso Peptide That Stops Bacteria in Their Tracks Common infections become deadly because the bacteria causing them have learned to resist our best medicines. This is the growing crisis of antibiotic resistance . Scientists are urgently looking for n... Chemistry Medicine NIH Funded
